Etofenamate

Etofenamate
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Topical (cream, gel, spray)
ATC code	M02AA06 (WHO) ;
Legal status
Legal status	In general: Over-the-counter (OTC);
Pharmacokinetic data
Protein binding	98–99%
Metabolites	Flufenamic acid, hydroxyl derivatives
Excretion	35% renal, mostly biliary
Identifiers
	IUPAC name 2-(2-hydroxyethoxy)ethyl 2-[ [3-(trifluoromethyl)phenyl]amino]benzoate;
CAS Number	30544-47-9 ;
PubChem CID	35375;
DrugBank	DB08984 ;
ChemSpider	32560 ;
UNII	KZF0XM66JC;
KEGG	D04102 ;
CompTox Dashboard (EPA)	DTXSID2045448 ;
ECHA InfoCard	100.045.650
Chemical and physical data
Formula	C18H18F3NO4
Molar mass	369.340 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES FC(F)(F)c1cc(ccc1)Nc2ccccc2C(=O)OCCOCCO;
	InChI InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2 ; Key:XILVEPYQJIOVNB-UHFFFAOYSA-N ;
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Etofenamate

NSAID analgesic medication

Etofenamate is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.^[1] It is available for topical application as a cream, a gel or as a spray.

Quick Facts Clinical data, AHFS/Drugs.com ...

Etofenamate is acutely toxic if swallowed; it is also very toxic to aquatic life, with long lasting effects.^[2]^{[unreliable medical source?]}

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This article uses material from the Wikipedia article Etofenamate, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[1] [1]
Chlud K (1999). "[Use of topical non-steroidal anti-inflammatory drugs in aggravated and decompensated arthroses]". Wiener Medizinische Wochenschrift (in German). 149 (19–20): 546–7. PMID 10637963.

[2] [2]
"Etofenamate". PubChem.

[1]

[2]

Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Topical (cream, gel, spray)
ATC code	M02AA06 (WHO)
Legal status
Legal status	In general: Over-the-counter (OTC)
Pharmacokinetic data
Protein binding	98–99%
Metabolites	Flufenamic acid, hydroxyl derivatives
Excretion	35% renal, mostly biliary
Identifiers
IUPAC name 2-(2-hydroxyethoxy)ethyl 2-[ [3-(trifluoromethyl)phenyl]amino]benzoate
CAS Number	30544-47-9^Y
PubChem CID	35375
DrugBank	DB08984^Y
ChemSpider	32560^Y
UNII	KZF0XM66JC
KEGG	D04102^Y
CompTox Dashboard (EPA)	DTXSID2045448
ECHA InfoCard	100.045.650
Chemical and physical data
Formula	C₁₈H₁₈F₃NO₄
Molar mass	369.340 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES FC(F)(F)c1cc(ccc1)Nc2ccccc2C(=O)OCCOCCO
InChI InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2^Y Key:XILVEPYQJIOVNB-UHFFFAOYSA-N^Y
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Etofenamate

References

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