Ets_variant_2

ETV2
Identifiers
Aliases	ETV2, ER71, ETSRP71, Ets variant 2, ETS variant transcription factor 2
External IDs	OMIM: 609358 MGI: 99253 HomoloGene: 7308 GeneCards: ETV2
Gene location (Human)
Chr.	Chromosome 19 (human)
End	35,644,871 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	30,335,277 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; right lobe of liver; ; skin of abdomen; ; body of pancreas; ; right adrenal gland; ; left adrenal gland; ; body of stomach; ; canal of the cervix; ; ganglionic eminence; ; vagina;
	Top expressed in
	urethra; ; male urethra; ; primitive streak; ; morula; ; seminiferous tubule; ; pharynx; ; yolk sac; ; spermatid; ; otic placode; ; ovary;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	Notch signaling pathway; cell differentiation; positive regulation of endothelial cell differentiation; regulation of transcription, DNA-templated; blood vessel morphogenesis; placenta development; regulation of transcription by RNA polymerase II; mesoderm formation; in utero embryonic development; Wnt signaling pathway; transcription by RNA polymerase II; positive regulation of mesoderm development; positive regulation of gene expression; BMP signaling pathway involved in mesodermal cell fate specification; erythrocyte differentiation; blastocyst development; positive regulation of transcription by RNA polymerase II; hemopoiesis;
	Sources:Amigo / QuickGO
Orthologs
	2116
	14008
	ENSG00000105672
	ENSMUSG00000006311
	O00321
	P41163
	NM_001300974; NM_001304549; NM_014209
	NM_007959
	NP_001287903; NP_001291478; NP_055024
	NP_031985
	Wikidata
View/Edit Human	View/Edit Mouse

Ets variant 2

Protein-coding gene in the species Homo sapiens

Ets variant 2 is a protein that in humans is encoded by the ETV2 gene.^[5] It is a transcription factor and also plays a role in vascular endothelial cell development.^[6]

Quick Facts ETV2, Identifiers ...

Share this article:

This article uses material from the Wikipedia article Ets_variant_2, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000105672 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000006311 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] [5]
"Entrez Gene: Ets variant 2".

[6] [6]
Oh SY, Kim JY, Park C (December 2015). "The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell Development". Molecules and Cells. 38 (12): 1029–36. doi:10.14348/molcells.2015.0331. PMC 4696993. PMID 26694034.

[5]

[6]

[1]

[2]

[3]

[4]

Ets_variant_2

References

Share this article: