Crespo was originally drafted by the Toronto Blue Jays in the third round of the 1990 Major League Baseball Draft.[1] He began his professional career in the minor leagues in 1991, and spent the next five full seasons there. Crespo reached the majors in 1996 with the Blue Jays, playing for them until 1998 before joining the San Francisco Giants (2000-2001), and Philadelphia Phillies (2001). His most productive season came in 2000 with San Francisco, when he hit .290, with four home runs, and 29 runs batted in (RBI), in 89 games – all career-highs.
On June 7, 2001, Crespo hit two home runs for the Giants, while his brother César hit his first major league homer with the San Diego Padres, joining a select club that includes Aaron and Bret Boone, Héctor and José Cruz, Al and Tony Cuccinello, Dom and Joe DiMaggio, Graig and Jim Nettles, Rick and Wes Ferrell, and Kyle and Corey Seager. The seven sets of brothers hit their homers playing for opposing teams.
In a five-season career, Crespo was a .245 hitter (109-for-445) with 10 home runs and 68 RBI in 262 games, including 46 runs, 22 doubles, four triples, and nine stolen bases.
Following Crespo's MLB career, he played in Japan for the 2002 Yomiuri Giants of the Central League.
