Fred Guiol (February 17, 1898 – May 23, 1964), pronounced "Gill," was an American film director and screenwriter.

Guiol worked at the Hal Roach Studios for many years, first as a property man, later as assistant director and finally writer and director. He directed Laurel and Hardy's earliest short films, as their famous comic partnership gradually developed during 1927.^[1] Guiol directed many of Hal Roach's Streamliners in the 1940s.

Guiol had worked closely with another Roach employee, cameraman George Stevens. When Stevens became a director in the 1930s, he often engaged Guiol as a screenwriter, Guiol, along with Ivan Moffat,was nominated for an Academy Award for Best Adapted Screenplay for adapting Edna Ferber's novel Giant into the George Stevens production of Giant.^[2]

Fred Guiol is buried in Forest Lawn Memorial Park in Glendale, California.