GDP-D-glucose_phosphorylase

GDP-D-glucose phosphorylase

GDP-D-glucose phosphorylase

Class of enzymes

GDP-D-glucose phosphorylase (EC 2.7.7.78) is an enzyme with systematic name GDP:alpha-D-glucose 1-phosphate guanylyltransferase.[1] This enzyme catalyses the following chemical reaction

GDP-alpha-D-glucose + phosphate alpha-D-glucose 1-phosphate + GDP
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The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates.

References

  1. [1]
    Adler LN, Gomez TA, Clarke SG, Linster CL (June 2011). "A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals". The Journal of Biological Chemistry. 286 (24): 21511–23. doi:10.1074/jbc.m111.238774. PMC 3122210. PMID 21507950.
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