Gerard_Kleywegt

Gerard Kleywegt

Gerard Kleywegt

Dutch X-ray crystallographer

Gerard Jacob Kleywegt (born 5 June 1962, in Rozenburg) is a Dutch X-ray crystallographer and the former team leader of the Protein Data Bank in Europe at the EBI;[1][2][3][4] a member of the Worldwide Protein Data Bank.[5][6]

Quick Facts Born, Nationality ...

Education

Kleywegt obtained his PhD from the University of Utrecht in 1991.

Career

After his PhD, Kleywegt did postdoctoral research with Alwyn Jones at Uppsala University.[7][8] before moving to the EBI.

Research

Kleywegt's research focuses on protein crystallography[9][10][11] and the Protein Data Bank.[12][13][14][15][16][17][18]

References

  1. [1]
    "Looking back on 2016".
  2. [2]
    "Gerard Kleywegt research group page at the EBI". Archived from the original on 2014-10-20.
  3. [3]
    Garwoord, Jeremy (May 2009) "A Guardian of Structural Integrity". Lab Times. pp. 19-23
  4. [4]
    Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi:10.1038/463425c. PMC 4456675. PMID 20110969.
  5. [5]
    Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cozzetto, D; Dana, J. M.; Filippis, I; Gough, J; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mistry, J; Murzin, A. G.; Ochoa-Montaño, B; Oates, M. E.; Punta, M; Rackham, O. J.; Stahlhacke, J; Sternberg, M. J.; Velankar, S; Orengo, C (2015). "Genome3D: Exploiting structure to help users understand their sequences". Nucleic Acids Research. 43 (Database issue): D382-6. doi:10.1093/nar/gku973. PMC 4384030. PMID 25348407.
  6. [6]
    Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cuff, A; Dana, J. M.; Filippis, I; Gough, J; Hunter, S; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mitchell, A; Murzin, A. G.; Ochoa-Montaño, B; Rackham, O. J.; Smith, J; Sternberg, M. J.; Velankar, S; Yeats, C; Orengo, C (2013). "Genome3D: A UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains". Nucleic Acids Research. 41 (Database issue): D499-507. doi:10.1093/nar/gks1266. PMC 3531217. PMID 23203986.
  7. [7]
    Jones, T. A.; Kleywegt, G. J. (2007). "Experimental Data for Structure Papers". Science. 317 (5835): 194c. doi:10.1126/science.317.5835.194c.
  8. [8]
    Kleywegt, G. J.; Jones, T. A. (1996). "Phi/psi-chology: Ramachandran revisited". Structure. 4 (12): 1395–400. doi:10.1016/s0969-2126(96)00147-5. PMID 8994966.
  9. [9]
    Read, R. J.; Adams, P. D.; Arendall Wb, 3rd; Brunger, A. T.; Emsley, P; Joosten, R. P.; Kleywegt, G. J.; Krissinel, E. B.; Lütteke, T; Otwinowski, Z; Perrakis, A; Richardson, J. S.; Sheffler, W. H.; Smith, J. L.; Tickle, I. J.; Vriend, G; Zwart, P. H. (2011). "A new generation of crystallographic validation tools for the protein data bank". Structure. 19 (10): 1395–412. doi:10.1016/j.str.2011.08.006. PMC 3195755. PMID 22000512.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  10. [10]
    Read, R. J.; Kleywegt, G. J. (2009). "Case-controlled structure validation". Acta Crystallographica Section D. 65 (Pt 2): 140–7. doi:10.1107/S0907444908041085. PMC 2631636. PMID 19171969.
  11. [11]
    Kleywegt, G. J.; Read, R. J. (1997). "Not your average density". Structure. 5 (12): 1557–69. doi:10.1016/s0969-2126(97)00305-5. PMID 9438862.
  12. [12]
    Montelione, G. T.; Nilges, M; Bax, A; Güntert, P; Herrmann, T; Richardson, J. S.; Schwieters, C. D.; Vranken, W. F.; Vuister, G. W.; Wishart, D. S.; Berman, H. M.; Kleywegt, G. J.; Markley, J. L. (2013). "Recommendations of the wwPDB NMR Validation Task Force". Structure. 21 (9): 1563–70. doi:10.1016/j.str.2013.07.021. PMC 3884077. PMID 24010715.
  13. [13]
    Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "How community has shaped the Protein Data Bank". Structure. 21 (9): 1485–91. doi:10.1016/j.str.2013.07.010. PMC 4435976. PMID 24010707.
  14. [14]
    Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "The future of the protein data bank". Biopolymers. 99 (3): 218–22. doi:10.1002/bip.22132. PMC 3684242. PMID 23023942.
  15. [15]
    Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2012). "The Protein Data Bank at 40: Reflecting on the past to prepare for the future". Structure. 20 (3): 391–6. doi:10.1016/j.str.2012.01.010. PMC 3501388. PMID 22404998.
  16. [16]
    Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi:10.1038/463425c. PMC 4456675. PMID 20110969.
  17. [17]
    Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "The Protein Data Bank archive as an open data resource". Journal of Computer-Aided Molecular Design. 28 (10): 1009–14. doi:10.1007/s10822-014-9770-y. PMC 4196035. PMID 25062767.
  18. [18]
    Berman, H. M.; Burley, S. K.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "Response to on prompt update of literature references in the Protein Data Bank". Acta Crystallographica Section D. 70 (Pt 10): 2780. doi:10.1107/S1399004714020513. PMC 4984264. PMID 25286863.
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