Greyhound Motors, later known as Bristol Greyhound, was an English bus and coach company based in Bristol.

Greyhound Motors was formed in February 1921 by Sydney Tom Toogood^[1] to operate motor buses in Bristol.

In February 1925, it commenced a long-distance coach service between Bristol and London, which has been claimed to be the first long-distance coach service with scheduled stops en route to pick up and set down passengers.^[2][3] The journey time was eight hours.^[4][5] It later began services from Bristol to Bournemouth and Paignton, and from London to Bournemouth.^[6] It also continued to run local bus services in Bristol, competing fiercely with Bristol Tramways.

In 1928, the company was acquired by Bristol Tramways. Greyhound continued to operate as a separate business, including its bus routes in Bristol until 1936.^[7][8] The new owners expanded the Greyhound coach operations. In 1934 it was one of the founder members of the Associated Motorways consortium of long-distance coach operators, but continued the London service outside the consortium.

At the beginning of 1936, the company's business was absorbed into Bristol Tramways.^[9] Bristol Omnibus Company continued to use the Greyhound name for its long-distance coach services until 1972, when the National Bus Company required Bristol to adopt the new National Express brand.^[10]

Shortly before its demise, on 9 January 1972 Greyhound Motors commenced operating an express Bristol to London service via the new M4 motorway.^[11]

In August 2009, FirstGroup who had owned the former Bristol Omnibus Company since April 1988, announced the reintroduction of the Greyhound brand in the United Kingdom.^[12] The new Greyhound UK was a byproduct of FirstGroup purchasing the Greyhound Lines business in the United States in February 2007.^[13] Greyhound UK also connected Bristol with Swansea and Bristol Airport until March 2015.^[14][15] This was the last Greyhound service operated.