Hartley House, formerly known as Hartley House Settlement, is a not for profit corporation, operating since 1897 as a charity serving the Hell's Kitchen neighborhood of Manhattan in New York City. Since its founding, the Hartley House has been operating from 413 West 46th Street in Manhattan.

The Hartley Farms are affiliated with the Hartley House Settlement.

• May Mathews was Executive Director of Hartley House for 50 years, beginning in the early 1900s following her graduation from Wellesley. Her dedication was commemorated by the naming of a neighborhood playground in her honor.
• Grace Hartley Jenkins Mead (1896–1991) was president of Hartley House from 1940 to 1965; she was the great granddaughter of Robert Milham Hartley^[1][2]

• Lincoln House Settlement – 202 W 63rd Street, Manhattan; founded by the leaders of the Henry Street Settlement to serve New York's African American community^[3]
• Henry Street Settlement – Lower East Side, Manhattan; founded in 1893 by Lillian Wald
• Third Street Settlement – 235 E 11th Street, now called Third Street Music School Settlement; founded in 1894 by Emilie Wagner
• Lenox Hill Neighborhood House – 331 E 70th Street; founded in 1894 by the Alumnae Association of Hunter College
• University Settlement House – the oldest settlement house in the United States, founded in 1886 by Stanton Coit, Charles B. Stover, and Carl Schurz
• Union Settlement Association – founded in 1895 by alumni, faculty, and students of Union Theological Seminary at 202 E 69th Street in response to the desperate conditions of immigrants struggling to make a new life in America ... within five months, the agency moved to its present site at 237 E 104th Street

• Settlement movement