Hydroxynefazodone

Hydroxynefazodone

Hydroxynefazodone

Chemical compound

Hydroxynefazodone is a phenylpiperazine compound and a major metabolite of the antidepressant nefazodone.[1][2][3] It has similar biological activity and a similar elimination half-life (1.5 to 4 hours)[1] to those of nefazodone, and may contribute significantly to its effects.[2][3]

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See also

References

  1. [1]
    Golden RN, Dawkins K, Nicholas L (2017). "Trazodone and Nefazodone". In Schatzberg AF, Nemeroff CB (eds.). The American Psychiatric Association Publishing Textbook of Psychopharmacology (Fifth ed.). American Psychiatric Pub. pp. 460–. ISBN 978-1-58562-523-9.
  2. [2]
    Preskorn SH, Catterson ML (6 December 2012). "General Principles of Pharmacokinetics". In Preskorn SH, Stanga CY, Feighner JP, Ross R (eds.). Antidepressants: Past, Present and Future. Springer Science & Business Media. pp. 68–. ISBN 978-3-642-18500-7.
  3. [3]
    Davis R, Whittington R, Bryson HM (April 1997). "Nefazodone. A review of its pharmacology and clinical efficacy in the management of major depression". Drugs. 53 (4): 608–636. doi:10.2165/00003495-199753040-00006. PMID 9098663. S2CID 239077479.
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