Inflammatory_reflex
Inflammatory reflex
Neural circuit on immune system
The inflammatory reflex is a neural circuit that regulates the immune response to injury and invasion. All reflexes have an afferent and efferent arc. The Inflammatory reflex has a sensory afferent arc, which is activated by cytokines, and a motor or efferent arc, which transmits action potentials in the vagus nerve to suppress cytokine production. Increased signaling in the efferent arc inhibits inflammation and prevents organ damage.
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It has also been shown that the brain can use this circuit not only to regulate the immune response but also to extend the immunological memory[1][2]