Iowa Highway 22 (Iowa 22) is a 98-mile (158 km) west–east state highway that traverses primarily rural areas in east-central Iowa. The highway begins near Thornburg at an intersection with Iowa Highway 21 and ends in southwestern Davenport, at U.S. Highway 61 Business.

Quick Facts Route information, Length ...

Iowa Highway 22
Iowa 22 highlighted in red
Route information
Maintained by Iowa DOT
Length	97.905 mi[1] (157.563 km)
Major junctions
West end	Iowa 21 in Thornburg
Major intersections	US 218 / Iowa 27 at Riverside US 61 / Iowa 38 at Muscatine I-280 at Davenport
East end	US 61 Bus. in Davenport
Location
Country	United States
State	Iowa
Counties	Keokuk Washington Johnson Muscatine Scott
Highway system
Iowa Primary Highway System Interstate US State Secondary Scenic
← Iowa 21 → Iowa 23

Close

Iowa Highway 22 begins west of Thornburg at Iowa Highway 21. It continues east through Keswick and Webster. Between Webster and South English, Iowa 22 is overlapped with Iowa Highway 149. It continues east from South English through Kinross and Wellman before intersecting Iowa Highway 1 at Kalona. It proceeds east from Kalona to go through Riverside and then intersects U.S. Highway 218 and Iowa Highway 27. After crossing the Iowa River, it goes through Nichols, where a short overlap with Iowa Highway 70 begins. It then continues eastward and intersects U.S. Highway 61 at Muscatine. It goes around the west and north city limits of Muscatine before intersecting Iowa Highway 38 and Business US 61 and turns south into Muscatine. It then turns east along a route next to the Mississippi River and passes through Buffalo before intersecting Interstate 280 at Davenport. It then turns north to end at U.S. 61.

To locals, Iowa Highway 22 is most notable as one of two main highways connecting Muscatine and Davenport (U.S. Highway 61 being the other). This 24-mile (39 km) eastern section of highway follows the Mississippi River.

The segment of the highway between Muscatine and Davenport is part of the Great River Road.

Iowa Highway 22 was designated in 1926, and followed what is now U.S. Highway 61 between Muscatine and Davenport, passing through Blue Grass; U.S. 61 followed the Mississippi River route at the time. The highway was extended to Thornburg in 1931.

For years, several sections of Iowa Highway 22 was either gravel or had a bituminous surface. One of these sections — the section between Muscatine and Blue Grass — was paved in 1957, the same year U.S. 61 and Iowa Highway 22 switched routes; U.S. 61 now went through Blue Grass, while Iowa Highway 22 now followed the Mississippi River through Buffalo.

The last segment — between U.S. Highway 218 east of Riverside to Iowa Highway 405 north of Lone Tree, was upgraded from bituminous to paved in 1988.