Jakob Stämpfli (23 February 1820 – 15 May 1879) was a Swiss politician and member of the Swiss Federal Council (1854–1863).

He was elected to the Federal Council of Switzerland on 6 December 1854, and handed over office on 31 December 1863. He was affiliated with the Free Democratic Party of Switzerland.

During his time in office he held the following departments:

• Department of Justice and Police (1855)
• Political Department as President of the Confederation (1856)
• Department of Finance (1857–1858)^[1]
• Political Department as President of the Confederation (1859)
• Military Department (1860–1861)
• Political Department as President of the Confederation (1862)
• Military Department (1863)

Jakob Stämpfli was also member of the international tribunal that had to decide on the Alabama Claims in 1871.