Los Angeles Dodgers

On May 31, 2013, Mieses signed with the Los Angeles Dodgers organization as an international free agent.^[1] He made his professional debut with the Dominican Summer League Dodgers, hitting .222 in 16 games. In 2014, Mieses returned to the DSL Dodgers, batting .299/.371/.505 with 5 home runs and 24 RBI in 59 games. Mieses split the 2015 season between the Single-A Great Lakes Loons and the High-A Rancho Cucamonga Quakes, accumulating a .260/.309/.439 batting line with 11 home runs and 39 RBI. The following year, Mieses returned to Rancho Cucamonga and hit .247/.314/.510 with career-highs in home runs (28) and RBI (78). In 2017, Mieses split the season between Rancho Cucamonga and the Double-A Tulsa Drillers, posting a .215/.293/.449 slash line with 24 home runs and 63 RBI.^[2]

St. Louis Cardinals

On April 1, 2018, the Dodgers traded Mieses to the St. Louis Cardinals in exchange for Breyvic Valera.^[3] Mieses split the 2018 season between the High-A Palm Beach Cardinals and the Double-A Springfield Cardinals, posting a .229/.283/.400 slash line with 19 home runs and 71 RBI in 122 games. In 2019, Mieses split the year between the Triple-A Memphis Redbirds and Springfield, slashing .233/.319/.440 with 22 home runs and 66 RBI in 118 games. On November 4, 2019, he elected free agency.

Boston Red Sox

On November 13, 2019, Mieses signed a minor league contract with the Boston Red Sox organization.^[4] Mieses did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.^[5] He was assigned to the Double-A Portland Sea Dogs to begin the 2021 season, and received a promotion to the Triple-A Worcester Red Sox in June. Mieses elected free agency following the season, but was later re-signed to a minor league deal on January 4, 2022.^[6]

Mieses played in 60 games for Triple–A Worcester in 2022, hitting .271/.387/.537 with 12 home runs, 35 RBI, and 5 stolen bases. He elected free agency following the season on November 10, 2022.^[7]

Hanshin Tigers

On December 15, 2022, Mieses signed with the Hanshin Tigers of Nippon Professional Baseball.^[8] Before he made his NPB debut, he briefly returned home in April 2023 after suffering a misfortune in his family.^[9] Mieses re-signed a one-year contract for the 2024 season on November 30, 2023.^[10]