Knowsley North was a borough constituency represented in the House of Commons of the Parliament of the United Kingdom from 1983 until 1997. It elected one Member of Parliament (MP) by the first past the post voting system.

The constituency was a safe seat for the Labour Party throughout its existence. Originally, it was represented by Robert Kilroy-Silk, who resigned in 1986 to pursue a media career. This resignation prompted a by-election, which was won by George Howarth.

The Metropolitan Borough of Knowsley wards of Cantril Farm, Cherryfield, Kirkby Central, Knowsley Park, Northwood, Park, Prescot East, Prescot West, Tower Hill, and Whitefield.

The constituency covered the northern part of the metropolitan borough of Knowsley, principally the town of Kirkby. Following a review by the Boundary Commission for England in 1995, the constituency was expanded at the 1997 general election to form the new Knowsley North and Sefton East constituency.

• 1986 Knowsley North by-election