Laos competed, officially as the Lao People's Democratic Republic, at the 2012 Summer Paralympics in London, United Kingdom, from August 29 to September 9. It was the country's third participation in the Paralympic Games.

Laos was represented by a single athlete, Eay Simay in powerlifting. Simay took part in his third Paralympics; at the Beijing Games in 2008, he won Laos' first Paralympic medal, a bronze.^[1]

Eay Simay competed in the men's under 48kg event.^[1]

• Summer Paralympic disability classification
• Laos at the Paralympics
• Laos at the 2012 Summer Olympics