Lipoyl_amidotransferase

Lipoyl amidotransferase

Lipoyl amidotransferase

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Lipoyl amidotransferase (EC 2.3.1.200, LipL (gene)) is an enzyme with systematic name (glycine cleavage system H)-N6-lipoyl-L-lysine:(lipoyl-carrier protein)-N6-L-lysine lipoyltransferase.[1] This enzyme catalyses the following chemical reaction

[glycine cleavage system H]-N6-lipoyl-L-lysine + [lipoyl-carrier protein] glycine cleavage system H + [lipoyl-carrier protein]-N6-lipoyl-L-lysine

In the bacterium Listeria monocytogenes the enzyme takes part in a pathway for scavenging of lipoic acid.


References

  1. Christensen QH, Hagar JA, O'Riordan MX, Cronan JE (September 2011). "A complex lipoate utilization pathway in Listeria monocytogenes". The Journal of Biological Chemistry. 286 (36): 31447–56. doi:10.1074/jbc.m111.273607. PMC 3173067. PMID 21768091.

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