This is a list of on-air personalities from the professional wrestling television series WWE's SmackDown. On-air personalities include the wrestlers themselves, ring announcers, commentators, and on-screen authority figures. The show also features recurring on-air segments hosted by various personalities.

• ^ Filled in for Jerry Lawler, who was absent at the time.
• ^ Filled in for Tazz, who was absent at the time.
• ^ Cole and Booker was absent at the time during WrestleMania week, so both men were replaced by Striker to call the event.
• ^ Mathews was absent at the time after being attacked by Brock Lesnar on the April 23, 2012 episode of Raw, so only Cole and Booker called the event.
• ^ Booker was absent at the time, so only Mathews and Cole called the event.
• ^ Following the absence of Josh Mathews, Michael Cole was joined by various guest commentators for one night on SmackDown. The following is a list of the guest commentators who joined Michael Cole on the August 24, 2012 episode of SmackDown:

• ^ Cole and JBL was absent due to the live report from WrestleMania Axxess, so both men were replaced by Lawler to call the event.^[4]
• ^ Filled in for JBL, who was absent at the time.
• ^ JBL was absent at the time, so only Phillips and Cole called the event.
• ^ Saxton was absent due to a live prediction about the upcoming matches at WrestleMania with Renee Young, so only two men called the event.^[5][6]
• ^ Filled in for Michael Cole, who was recovering from injury after being attacked by Brock Lesnar on the March 30, 2015 episode of Raw.^[7]
• ^ Filled in for Byron Saxton, who joined Raw as a color commentator since June 8, 2015.
• ^ Replaced Booker T as announced on Raw on January 4, 2016.
• ^ Ranallo was absent due to suffering from influenza and was filled in by Michael Cole from Monday Night Raw on February 18, 2016.
• ^ Due to Lawler being suspended, he was filled in by David Otunga from Main Event and Superstars for two weeks.
• ^ Michael Cole was representing Raw for the 2016 WWE draft.
• ^ Announced as the new commentary team following the 2016 WWE Draft Lottery.^[8]
• ^ When Ranallo was absent due to suffering from depression, Tom Phillips filled in for him as play-by-play.
• ^ Saxton temporarily joined the commentary team following the 2017 WWE Superstar Shake-up.
• ^ When Tom Phillips was on assignment, he was filled in by Raw's Michael Cole.
• ^ Otunga filled in for Byron Saxton, who was absent at the time.
• ^ On November 1, 2019, due to significant flight delays returning from the Crown Jewel event in Riyadh, Saudi Arabia, more than 100 WWE employees were not able to travel to Buffalo, New York in time to appear on Smackdown Live on Fox. In response, WWE featured multiple NXT superstars who did not travel to Saudi Arabia. McAfee was among them as guest color commentary, joining Renee Young and Tom Phillips, while replacing Aiden English.
• ^ Filled in for Pat McAfee, who was recovering from COVID-19.
• ^ Pat McAfee stepped away from SmackDown to provide coverage for College GameDay.
• ^ Filled in for Corey Graves, who was away due to the birth of his son.
• ^ Replaced Corey Graves for Tribute to the Troops

• List of WWE Raw on-air personalities
• List of current champions in WWE