This list of historical markers installed by the National Historical Commission of the Philippines (NHCP) in SOCCSKSARGEN (Region XII) is an annotated list of people, places, or events in the region that have been commemorated by cast-iron plaques issued by the said commission. The plaques themselves are permanent signs installed in publicly visible locations on buildings, monuments, or in special locations.

While many Cultural Properties have historical markers installed, not all places marked with historical markers are designated into one of the particular categories of Cultural Properties.

This article lists four (4) markers from the SOCCSKSARGEN, including two (2) that are part of the Quincentennial historical markers series.

This article lists no markers from the Province of Cotabato. A marker commemorating Fort Pikit, while geographically located in the province, is part of the Bangsamoro Autonomous Region in Muslim Mindanao (BARMM) as a Special Geographic Area.

This article lists two (2) markers from the Province of Sarangani.

This article lists two (2) markers from the Province of South Cotabato.

This article lists no markers from the Province of Sultan Kudarat.

• List of Cultural Properties of the Philippines in Soccsksargen