2016

In 2016, Marini was signed by the Forward Team to compete full-time in the same class; he got his first Grand Prix points in Qatar, where he finished in 10th place, and his best result in Germany, where he had a 6th-place finish. Marini still remained with the team for

2017

In 2017, Marini was signed Forward Team. Finished in 4th place, Czech Republic.

2018

In 2018, Marini achieved his first podium in Germany and his first victory in Malaysia.

2019

In 2019, he secured two podiums in Mugello and Assen, leading to back-to-back wins at Thailand and Japan.

2020

In 2020 Marini became a contender for the championship title along with Enea Bastianini and Sam Lowes, the first round of the season saw Marini retire at Qatar but would clinch his first win at the second round at the Spanish Grand Prix and claim a second-place finish in the second Jerez round (the Andalusian GP), with more point scoring finishes at Brno (4th place) and another second-place finish at the Austrian Grand Prix and a point finish in Styria before claiming his second win and a 4th place respectively at the two Misano rounds before adding a third win at Catalunya.

Marini finished the French Grand Prix outside the points in 18th and at the first Aragon round he highsided off his bike and retired from the race with Lowes taking first place in the next three rounds with Marini finishing the same three rounds (Teruel, Europe, and Valencia) in 11th, 6th and 5th place respectively and finishing 2nd in Portugal behind Remy Gardner who would claimed his first win.

Marini finished the 2020 Moto2 season as the championship runner up with 196 points with over three wins and three 2nd place finishes which put Marini ahead of Lowes who had scored exactly the same points as Marini but Lowes claimed third and Marini second at the final race which meant that Marini was ahead of Lowes on countback, with Bastianini being nine points ahead of both of them.