The Institute of Medical Specialties receives 20 children injured because of a car accident caused by a heart attack suffered by Braulio while driving. Dr. Lara announces to the parents the health status of the victims. Regina and Gonzalo manage to stabilize an injured person from the accident. Aníbal asks Dr. Lara for help to check on his son, who was also a victim of the car accident, but he is denied medical attention. René along with Mireya, divert cannulas and medical resources to sell them to the black market. The next day, Aníbal returns to the hospital with his son in a critical condition, but doctors give him no hope, because he had internal injuries that affected his son's organs. Aníbal tells the doctors that he took his son for a check-up, which Dr. Lara denied, giving him a negligent situation on the part of the doctor. Aníbal, believing that his son was killed by Dr. Lara, runs towards the doctor in a fit of rage and slaps him, but doctors restrain him and expel him from the hospital under Dr. Lara's orders. Later, Dr. Lara enters his office, which to his surprise he finds Aníbal, in order to avenge the death of his son, kills Dr. Lara with a shot.

Dr. Lara dies on the way to the operating room, after the bullet Aníbal hit him in the head with. René blames Gonzalo for what happened, and for not having order in the emergency department. To which Sergio asks to spend more time together with Regina. The hospital board of directors meets to see who stays as the new hospital director.

Ana does not agree that Gonzalo is the director and René will try to remove him from the position. Gonzalo appoints Regina the new Chief of Emergency.

Ana and René conspire against Gonzalo. Susana is tired of dealing with the working life of Luis and Regina begins her work as Chief of Emergency.

Gonzalo welcomes three new residents to the Institute of Medical Specialties. Regina and Ana argue over staff management.

Regina upon arriving at her home, discovers Sergio having sex with a swinger couple. Sergio apologizes to Regina and tries to explain how the situation was, but she kicks him out of the house. The next day, for staying talking with Sergio for a while, Regina forgets her meeting with Ana. Later, Ana asks Regina to respect her schedules and accuses her with Gonzalo to do her job well as emergency chief.

Regina, distraught with what happened with Sergio, talks to Gonzalo to tell her that she resigns the position of chief of emergency, because she does not have the most concentration due to Sergio cheating, to which Gonzalo refuses to receive her resignation as head and supports her morally. Regina asks Ana for a moment to review and sign the schedule with the rotations of the doctors who are going to support her, but she has a rude attitude and refuses to view the folder with the documents to be signed. Regina asks Ana to stop being rude, to which Ana asks to stop interfering in her area. Later, Luis goes through the files at Ana's office. Ana asks him to review half of the patients in the waiting room and teases him by telling him to finish as quickly as possible to spend more time with his family, to which Luis is not humiliated. Sergio with a bouquet of flowers waits for Regina at the end of her shift to apologize and for a new opportunity with her, but when she refuses, Sergio tries to kiss her by force, which David goes out to defend her.

Luis receives a patient who does not believe in vaccines. Sergio assures Regina that he will not stop fighting for her. David and Arturo fight in the emergency room.

David and Arturo argue while trying to save a patient's life, causing a scandal at the Institute of Medical Specialties.

Marco arrives believing himself superior to the residents, but Gonzalo and Regina lower him from his cloud. René has a plan to take over the hospital.

Both Ana and Regina are happy with David's medical support. Regina kicks out Sergio from the hospital and René asks Gonzalo to trust him.

Regina leaves the house and ends forever with Sergio. Also, confronts Mireya. A new patient with diabetic foot arrives.

Gonzalo informs the team of the budget cut that will be after losing the trial, a fact that unleashes a chaos in the Institute of Medical Specialties.

Ana threatens Regina after the budget cut. A new case will affect David. Mireya conspires against Regina with Fausto.

Inés arrives again with injuries to the Institute of Medical Specialties. Gonzalo invites Regina to live at his home; René and Mireya suspect of them.

Regina and Cynthia urgently attend Inés, who has returned unconscious and with severe injuries to the body.

Cecilia wants to recover what she had with Arturo and René is about to be discovered by Constanza.

Fausto publishes an article talking about the hospital. Rafael gets high again and Regina will see a patient who arrives with dehydration.

David defends Regina from Leo. Cecilia is diagnosed with anemia and Mireya conspires again against Gonzalo and Regina.

David yells at Tania for missing the guard and she feels disappointed. Mireya requires René to divorce his wife and Inés will make a decision.

René congratulates Gonzalo and Regina for their alleged "relationship." Arturo threatens Cecilia if she doesn't take care of herself. Ana questions David about Regina.

David tests Marco. Regina asks Gonzalo to move Mireya to another area and a famous fighter will arrive at the Institute of Medical Specialties.

Ana tries to seduce David, Mireya and Regina make peace and Cynthia informs Tirano that he won't be able to fight again.

Erika arrives very sick at the hospital and doctors do not find what she is suffering from. Mireya and René will remain united to attack Regina.

Tania invites Rafa to her house. Erika fears death and confesses the secret that afflicts her. Ana demands respect from Regina again.

Sergio attacks David and he responds to blows. Tania will suffer the contempt of a patient and Erika is already out of danger.

Rafa accepts Tania's invitation to go home. Cynthia's dad rejects her for not leaving the medicine.

Regina must attend impaled men and Luis tries to help Don Héctor, a man who is evicted.

Regina saves impaled men. Daniel catches Tania kissing with Rafa and David receives a summons because of Sergio.

Arturo asks David to leave Regina alone and, in addition, puts a stop to Cecilia's lies. Caro and Jime suffer an accident.

Victoria and Roberto, from Vega and associates, arrive at the hospital to help Regina and David with their cases.

Cynthia complains to Rafa for having kissed Tania. Victoria gets Sergio to accept Regina's divorce agreement.

René warns David that if he doesn't measure his attitude, he takes him out of the hospital. The death of Don Héctor causes a crisis to Pamela.

Tania tries to fix her friendship with Daniel. Arturo wants to be happy again and Roberto wins David's case.

David and Arturo argue for Regina's love. Rafa gets high again. Estela's case baffles the Institute of Medical Specialties.

Arturo organizes a Quinceañera party for his patient in the hospital. Rafa continues to raise suspicion for his behavior and someone tries to blackmail him.

David takes advantage of the congress to Puerto Vallarta to approach Regina. Arturo has the same intentions.

Regina is disappointed to find David with Ana. Arturo is honest with Regina and steals a kiss.

David looks for Regina and tries to talk to her. However, she confesses that she saw him with Ana.

Ana looks for David and tries to convince him to resume their relationship and give himself a new opportunity.

Regina punishes residents for the missing money. Gonzalo scolds René for the bad measures taken and a new case comes to the emergency room.

Gonzalo asks his son for an opportunity to be together. René accuses Gonzalo with Montesino and Diego confesses his robbery.

Arturo tells Cecilia that he does not want to see her again and she assures him that it will be so. Tania discovers Rafa's drugs.

Arturo is blamed for Cecilia's death. The institute enters a heat crisis causing severe damage.

René manages Montesinos to demand Gonzalo do his job. Victor insists on suing the institute and Arturo knows that Regina is the woman of his life.

David sees Regina and Arturo hugging. Diego confesses to having taken the material and Marco denounces it with René.

Victor insists on suing the hospital, especially now that Marco corroborates the doctors' mistake. Ana doesn't want David to continue suffering.

René assures Regina that if she does not control her team, he will take other measures. Gonzalo condones Diego for the robbery.

Regina believes that there is something between Ana and David. The transformer fails and the hospital runs out of light.

Gonzalo suspects that hospital problems are intentional. Gabriel, Luis's son, arrives ill in the ER.

Luis is afraid of what happens to his son. David overhears that Regina and Arturo kissed.

Regina confesses that she likes David. Ana investigates Rafa and Tania tells Cynthia that he is taking controlled medications.

Rafa confesses to Gonzalo and Cynthia that he is addicted to drugs and asks for help. Natalia questions Samuel about the relationship with her sister.

Rafa confesses his addiction to his teammates. Ana and Regina fight again and Paulina comes to save Gabriel's life.

The Undersecretary of Health empowers René to administer the hospital. Susana doesn't want Paulina to attend to her son.

David confesses to Regina being jealous of Arturo and kisses her. Natalia stabs her sister.

René fires Diego from the hospital in front of everyone. Gabriel gets worse and Susana blames Paulina for his severity.

David and Regina go out to dinner. Gabriel's life is in danger. Natalia surrenders to the authorities.

Luis tries to save his son, but Regina and Paulina say there is nothing to do; Susana blames Paulina for Gabriel's death.

Arturo explodes knowing that Regina and David are dating. Ana confesses to David her past and how much she needs him.

Arturo looks for David to tell him that he will be watching Regina. David feels threatened and sets a limit.

Gonzalo leaves the event after knowing that Aurora is hospitalized and René takes the opportunity to speak against him.

Javier leaves Aurora under Gonzalo's care. Ana asks Arturo to protect Regina from David.

Regina and David spend the night together; He declares his love. Mireya will not continue helping René.

Ana warns Regina about David and confesses that they had a relationship in the past. Luis does not overcome Gabriel's loss.

Carmen is found lying on the street and Rafa saves her. David confronts Ana for revealing their past relationship to Regina.

René and Mireya's plan to make Gonzalo removed from office works, accusing him of misusing the hospital's resources, meanwhile, Regina attends to a famous former singer with respiratory problems and a history of cancer.

The Undersecretary of Health ceases Gonzalo from his post and now René is the new director of the hospital.

Gonzalo knows that René is behind everything and confronts him; Alonso Vega decides to take his case.

René fires Gonzalo from the hospital and Pamela offers his help to Carmen to find her daughter.

René proposes Ana to be the new administrative director. Gonzalo and Aurora forgive each other and Regina argues with René.

Ana accepts René's proposal and takes advantage of her position to make adjustments in the ER. David and Arturo fight with blows.

Regina, pressured by René, dismisses David from the hospital and also ends her relationship with him.

Pamela discovers that Carmen is her mother. Ricardo will help in Gonzalo's case. Regina explodes against Mireya.

David returns to the hospital and learns that Regina preferred to fire him over Arturo.

Carlos requires Regina to attend to his client. Paulina visits Susana, Gonzalo and René will fight again.

Carlos requires Regina to attend El Ciego well and bribes René so that his client receives visits. Michelle and El Cuervo visit the offender.

Susana confesses to Luis that she still loves him. Ana sanctions the doctors and Michelle accepts El Ciego's deal.

Aurora gets worse and Gonzalo will seek to beat the treatment. El Ciego leaves the institute and Rafa wants something serious with Cinthia.

Ana insists with David to resume the relationship and Arturo tells Regina that he is the one for her. Ricardo seeks to unmask René.

Aurora decides to continue the treatment, René and Mireya are discovered by Constanza.

Constanza fights with Mireya and kicks out René from the house. Esteban hits Marco and a crisis invades the institute.

Gonzalo speaks with Vega and Associates to inform them of the relationship between Mireya and René. Ana helps Regina in the emergency room.

René dismisses Mireya in front of Constanza. Arturo reiterates his love for Regina. Marco's patient dies.

Regina receives a subpoena to testify. Vega y Asociados already has the strategy for defense and David suffers an accident.

Regina suffers from seeing David delicate and hands the proof to Vega and Associates to denounce René. An important witness will change the course of the trial against Gonzalo and a great secret from the hospital director will come to light.