Makati Avenue (Filipino: Abenida Makati) is a major commercial thoroughfare in Makati, Metro Manila, Philippines. It forms the eastern border of Ayala Triangle and is one of the three main avenues of the Makati Central Business District. The avenue runs in a somewhat north–south diagonal direction almost parallel with Epifanio de los Santos Avenue (EDSA). It passes through two distinct neighborhoods of the city: the Makati CBD and the old Makati Población. At its northern end lies the older part of Makati starting from J.P. Rizal Avenue. It continues through Población to Gil Puyat Avenue, marking the southern edge of the old district. South of Gil Puyat onto the CBD, the avenue becomes more commercial and upscale. The shopping hub of Ayala Center and Arnaiz Avenue lie at its southern end.

Makati Avenue has two lanes each way in the Poblacion area, widening to three or four in the CBD. It has a short extension into the gated San Lorenzo Village as San Lorenzo Drive.

Makati Avenue begins at the intersection of Arnaiz Avenue and San Lorenzo Drive in Barangay San Lorenzo, it passes through the Greenbelt and Glorietta complexes between its southern terminus to Ayala Avenue, where it enters Salcedo Village. The western part of the avenue is under the jurisdiction of Barangay Bel-Air while its Barangay Urdaneta is at the eastern part of the avenue.

After its intersection with Paseo de Roxas and Gil Puyat Avenue, the eastern part of the avenue enters Bel-Air until it passes Jupiter Street.

Makati Avenue enters Poblacion shortly after its intersection with Jupiter Street. It passes much of Poblacion between Kalayaan Avenue and J.P. Rizal Avenue.

It terminates at J.P. Rizal Avenue and continues to Mandaluyong as P. Burgos Street.

This section possibly contains original research. (June 2022)

The avenue served as the primary access road to the old Nielson Field airport from San Pedro de Macati. It was known as Culi-Culi Road which also led to the barrio of Culi-Culi (now Pio del Pilar) just west of Nielson Field.^[2][3] After the airport was closed down after World War II, its two runways were converted into wide roads known today as Ayala Avenue and Paseo de Roxas. The airport's control tower was preserved and is now a library called Filipinas Heritage Library.^[4] This library is located along the avenue at the southeast corner of Ayala Triangle.

Makati Avenue, particularly its northern segment in Poblacion, has a history of prostitution. The areas around P. Burgos Street with its nightclubs, bars and budget hotels are considered by many as the red light district of Makati.^{[5][better source needed]} At present, however, the area is undergoing gentrification with the completion of several new commercial developments including the Century City mall and complex.^{[6][original research?]}

The entire route is located in Makati. 

More information km, mi ...

km	mi	Destinations	Notes
		Arnaiz Avenue	Southern terminus. Traffic light intersection. Continues south into San Lorenzo Village as San Lorenzo Drive.
		Esperanza Street	Entrance only to Makati Avenue southbound
		Palm Drive	Traffic light intersection. Access to Glorietta and Greenbelt complexes.
		Parkway Drive	Traffic light intersection. Access to Glorietta complex.
		De la Rosa Street	Southbound access to Legazpi Village
		Ayala Avenue	Traffic light intersection
		Santo Tomas Street	Access to Urdaneta Village and The Peninsula Manila
		Paseo de Roxas	Traffic light intersection
		H.V. De la Costa Street	Traffic light intersection on the southbound side. Southbound access to Salcedo Village.
		Buendia Extension Access Road	Southbound access only towards Gil Puyat Avenue eastbound
		Cruzada Street	Northbound access only
		N190 (Gil Puyat Avenue)	Traffic light intersection. South end of DPWH maintenance.[7]
		Jupiter Street	No left turn allowed from both northbound and southbound. Access to Bel-Air Village.
		Juno Street	Restricted access to Bel-Air Village.
		Anza Street
		P. Burgos Street	Exit from Makati Avenue only. Access to the Red Light District and the old Makati Población
		Hercules Street	Restricted access to Bel-Air Village.
		Tigris Street
		Constellation Street	Restricted access to Bel-Air Village.
		Neptune Street, Durban Street	Both entrance to Makati Avenue only
		Kalayaan Avenue	Traffic light intersection
		Eduque Street
		General Luna Street	No left turn allowed from southbound and no right turn from northbound. Access to Century City.
		Guerrero Street
		Guanzon Street
		B. Valdez Street	No right turn allowed from southbound and no left turn from northbound. Access to Sts. Peter and Paul Parish Church and Saint Paul College of Makati.
		Singian Street	Unsignaled intersection
		P. Burgos Street	Northbound entrance only to Makati Avenue
		J.P. Rizal Avenue	Northern terminus; continues north towards Makati–Mandaluyong Bridge as P. Burgos Street. Traffic light intersection.
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Closed/former       Incomplete access

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Makati Avenue is a retail and entertainment hub of Makati. At its south end, the avenue bisects the Ayala Center, separating Glorietta, The Landmark department store and The Link shopping mall from the more upscale Greenbelt shopping center. This section of the avenue also hosts the Ayala Museum, Greenbelt Chapel, as well as several luxury hotels such as the Makati Shangri-La, Manila, Fairmont Hotel Manila, Raffles Hotel Manila, and New World Makati Hotel. The stretch from Ayala Avenue to Gil Puyat Avenue is the site of the Ayala Triangle Gardens, which houses the Old Nielson Tower and the future Park Central Towers. This section of the avenue also hosts The Peninsula Manila, Zuellig Building, Pacific Star Building, as well as several other office buildings.

North of Gil Puyat are more hotels and commercial establishments, particularly near the intersection with Kalayaan Avenue. The A. Venue Mall and Century City Mall are located in this area, as well as Gramercy Residences, Trump Tower Manila, Berjaya Makati Hotel, I'M Hotel Makati, St. Giles Hotel and Best Western Antel. The Sts. Peter and Paul Parish Church and Saint Paul College of Makati can be accessed by turning east onto Valdez Street before reaching J.P. Rizal Avenue and the Makati–Mandaluyong Bridge.