Maneb

Maneb

Maneb

Chemical compound

{{Chembox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 434399765 | ImageFile = Maneb.svg | ImageAlt = | IUPACName = [[2-[(Dithiocarboxy)amino]ethyl]carbamodithioato]](2-)-kS,kS']manganese | OtherNames = Manganese ethylene-1,2-bisdithiocarbamate, polymer |Section1=!Identifiers

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3D model (JSmol)

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| ECHA InfoCard | 100.032.400 Edit this at Wikidata |-



| MeSH | Maneb |-

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| UNII

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  • InChI=1S/C4H8N2S4.Mn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2
    Key: YKSNLCVSTHTHJA-UHFFFAOYSA-L

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  • [Mn+]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)[S-]

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| (C4H6MnN2S4)n

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| Appearance | Yellow to brown colored crystalline solid |-

| Density | 1.92 g/cm3 |- | Melting point | 192 to 204 °C (378 to 399 °F; 465 to 477 K) (decomposes)

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| 160 mg/L |- |Section3=!Hazards

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| GHS07: Exclamation markGHS08: Health hazardGHS09: Environmental hazard

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Maneb is a fungicide and a polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand.[1]

Health effects

See also: Manganism, Parkinsonism, and Parkinson's disease

Exposure to Maneb can irritate the eyes, nose, and throat. Prolonged or long-term exposure may interfere with the function of the thyroid.[2]

Production

Applications

It can be also used to create a toxin-based animal model of Parkinson's disease, usually in primates.[3]

Regulation

It was included in a pesticide ban proposed by the Swedish Chemicals Agency [4] and approved by the European Parliament on January 13, 2009.[5]

See also

References

  1. [1]
    Arno H. Reidies "Manganese Compounds" Ullmann's Encyclopedia of Chemical Technology 2007; Wiley-VCH, Weinheim. doi:10.1002/14356007.a16_123
  2. [2]
    "MANEB.doc" (PDF).
  3. [3]
    Cicchetti F, Drouin-Ouellet J, Gross RE (September 2009). "Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?". Trends Pharmacol. Sci. 30 (9): 475–83. doi:10.1016/j.tips.2009.06.005. PMID 19729209.
  4. [4]
    "Interpretation of criteria for approval of active substances in the proposed EU plant protection regulation". Swedish Chemicals Agency (KemI). 2008-09-23. Archived from the original on 2009-01-01. Retrieved 2009-01-14.
  5. [5]
    "MEPs approve pesticides legislation". 2009-01-13. Archived from the original on 2009-01-25. Retrieved 2009-01-14.
  • Maneb in the Pesticide Properties DataBase (PPDB)
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