Manuel Keosseian, in Armenian Մանուել Քեոսեյան, (born 17 August 1953 in Montevideo) is an Armenian Uruguayan former professional footballer who played as a midfielder. After he retired from playing, Keosseian became a manager and has led several clubs including Uruguayan side C.A. Peñarol.

Keosseian appeared for Aucas as a player, and would later manage in Ecuador with El Nacional.^[1]

Before Keosseian led the "Rojos" to the 2010 Guatemalan Clausura championship. In Peñarol, He made 75% of points in Southamerican Tournament (Copa Sudamericana 2010), 75% is more than % made by Aguirre in Libertadores 2011.^{[citation needed]} In the afternoon of 21 June 2010 he communicated to csD Municipal that he would be the new manager of C.A. Peñarol. this opportunity for Manolo is the best received in his entire career as a manager. Previously, he was the manager of Honduras's C.D. Marathón.,^[2] which he had led to league titles. manolo has a great vision of football. He suggested to Bella Vista of Montevideo, hire Egidio Arevalo Rios, Uruguayan midfielder of national team.^{[citation needed]}

Marathón

• Honduran Liga Nacional: 2007 Honduras Apertura, 2009 Honduras Apertura, 2010 Honduras Apertura

Municipal

• Guatemala Clausura: 2010