Mattapony is a former hundred in Worcester County, Maryland.

Mattapony and its various spellings (Mattaponi, Mataponi, Mattapany, Matapani) may also refer to:

• Mattaponi, an Algonquian tribe
• Mattaponi River, a tributary of the York River estuary in eastern Virginia
• Mattaponi, Virginia, an unincorporated community in King and Queen County, Virginia
• Mattaponi Wildlife Management Area, a state-managed protected area in Caroline County, Virginia
• USS Mattaponi (AO-41), the name of a United States Navy Mattaponi-class oiler
• Mataponi Creek, a tributary of the Patuxent River in Prince George's County, Maryland
• Camp Mataponi, an all-girls sleepaway camp in Naples, Maine
• Matapani, a settlement in Kenya's Coast Province
• Mattapany-Sewall Archeological Site, a registered historic place in St. Mary's County, Maryland
• Mattapony Creek, a tributary of the Pocomoke River in Worcester County, Maryland
• Mattaponi (John Bowie Jr. House) is a historic building in Nottingham, Prince George's County, Maryland

• Mattapan, Boston

This disambiguation page lists articles associated with the title Mattapony.
If an internal link led you here, you may wish to change the link to point directly to the intended article.