Melissa Brown is an ophthalmologist from Flourtown, Pennsylvania who is a member of the Republican Party. She was also a three-time candidate for the United States House of Representatives.

Born in Memphis, Tennessee, Melissa Brown attended Keuka College and graduated with a B.S. in Nursing in 1972. With a strong interest in education, she has been on the Keuka College Board of Trustees since 1992 and was elected chair in 2010.^[1] She subsequently received her master's degree in Nursing from Emory University and then taught on the faculty at the University of Pennsylvania.

She returned to Thomas Jefferson University where she earned her M.D. in 1982. After an internship at Chestnut Hill Hospital, she completed a residency in ophthalmology at Wills Eye Hospital. Brown obtained her MBA in Strategic Management from Saint Joseph's University's Haub School of Business in 1998. She is an adjunct Senior Fellow at the Leonard Davis Institute of Medical Economics at the University of Pennsylvania.

In 1998, Brown ran in the Republican primary in Pennsylvania's 13th congressional district against incumbent U.S. Rep. Jon Fox, and came in third.^[2]

She considered a run in 2000, but withdrew in favor of State Sen. Stewart Greenleaf.

Since the last election, Brown has returned to her medical practice and lecture work.