In the field of memetics, a metameme (or meta-meme) is defined as a meme about a meme. The very concept of memes themselves has been referred to as "the Metameme".^[1] Ideological tolerance and the rhetorical device of metaphor clearly fit this framing.^[1] Regarding the former, one may usefully expand:

A meta-meme which confers resistance to a wide variety of memes (and their sociotypes), without conferring meme-allergies. In its purest form, Tolerance allows its host to be repeatedly exposed to rival memes, even intolerant rivals, without active infection or meme-allergic reaction. Tolerance is a central co-meme in a wide variety of schemes, particularly "liberalism", and "democracy". Without it, a scheme will often become exo-toxic and confer meme-allergies on its hosts. Since schemes compete for finite belief-space, tolerance is not necessarily a virtue, but it has co-evolved in the ideosphere in much the same way as co-operation has evolved in biological ecosystems. (Henson.)^[1]

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Initial definitions of meta memes and the lingo surrounding the phenomenon have seen a recent overhaul, as a new perspective is beginning to emerge due to heightened interest from researchers and companies alike.

Metamemes may be used to measure the evolution of a given society. It has been proposed that the degree of consciousness a society has about the very memes that form it is correlated with how evolved that society is. The difficulties associated with measuring the "metamemetic content" of a given society, however, render that proposition impractical.

This can be viewed (to some extent) as a memetic approach to the American sociologist Gerhard Lenski's view that the more information a given society has, the more advanced it is.^{[citation needed]}

• Memeplex, Memetics and memetic engineering — clearly meta-memes