Mordechai Ish-Shalom (Hebrew: מרדכי איש-שלום‎), (1902–1991^[1]), was an Israeli politician and labor leader. He was the Mayor of West Jerusalem from 1959 to 1965.

Mordechai Ish-Shalom was born in Lithuania during the reign of the Russian Empire. He immigrated to Mandate Palestine in 1923. His labor career began in the Stonecutters' Union in 1935; he then rose through the ranks of the Histadrut, the Israeli trade union congress.^[1]

In 1964, Ish-Shalom established an interdisciplinary professional team to plan the modernization of Jerusalem.^[2]

In the 1970s, he was instrumental in the development of Kiryat Wolfson, a five-tower high-rise project overlooking Sacher Park.^[3]

Ish-Shalom died on 21 February 1991.^{[lower-alpha 1][1]}