Motile_sperm_domain_containing_2

Motile sperm domain containing 2

Motile sperm domain containing 2

Protein-coding gene in the species Homo sapiens

Motile sperm domain containing 2 is a protein that in humans is encoded by the MOSPD2 gene.[5] It is an endoplasmic reticulum–resident protein involved in membrane contact site formation.[6] Its domain homologous to Major Sperm Protein (MSP domain) is very similar to VAPA/VAPB, so it has been described as the third human member of the VAP protein family.

Quick Facts MOSPD2, Available structures ...

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000130150 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000061778 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    "Entrez Gene: Motile sperm domain containing 2".
  6. [6]
    Di Mattia T, Wilhelm LP, Ikhlef S, Wendling C, Spehner D, Nominé Y, Giordano F, Mathelin C, Drin G, Tomasetto C, Alpy F (June 2018). "Identification of MOSPD2, a novel scaffold for endoplasmic reticulum membrane contact sites". EMBO Reports. 19 (7): e45453. doi:10.15252/embr.201745453. PMC 6030701. PMID 29858488.

Further reading

  • PDBe-KB provides an overview of all the structure information available in the PDB for Mouse Motile sperm domain-containing protein 2
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