N-Desethyletonitazene

<i>N</i>-Desethyletonitazene

N-Desethyletonitazene

Chemical compound

N-Desethyletonitazene (NDE, Noretonitazene) is a benzimidazole derivative with potent opioid effects which has been sold as a designer drug. It is better known as an active metabolite of the related compound etonitazene, but has similar activity to the parent compound and has sometimes appeared as a drug of abuse in its own right,[1][2] being identified in New Zealand in 2024.[3][4]

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See also

References

  1. [1]
    Vandeputte MM, Van Uytfanghe K, Layle NK, St Germaine DM, Iula DM, Stove CP (April 2021). "Synthesis, Chemical Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of "Nitazene" 2-Benzylbenzimidazole Synthetic Opioids". ACS Chemical Neuroscience. 12 (7): 1241–1251. doi:10.1021/acschemneuro.1c00064. hdl:1854/LU-8714061. PMID 33759494. S2CID 232337929.
  2. [2]
    Pergolizzi Jr J, Raffa R, LeQuang JK, Breve F, Varrassi G (21 June 2023). "Old Drugs and New Challenges: A Narrative Review of Nitazenes". Cureus. 15 (6): e40736. doi:10.7759/cureus.40736. PMC 10361140. PMID 37485167.
  3. [3]
    "Highly potent synthetic opioid detected in fake diazepam tablet". High Alert. New Zealand Government. 2024.
  4. [4]
    Campbell G (9 May 2024). "N-Desethyletonitazene found in second fake tablet, this time in Tauranga". New Zealand Herald.


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