N1-acetylpolyamine_oxidase
N1-acetylpolyamine oxidase (EC 1.5.3.13, hPAO-1, mPAO, hPAO) is an enzyme with systematic name N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming).[1][2][3][4] This enzyme catalyses the following chemical reaction
- (1) N1-acetylspermidine + O2 + H2O putrescine + 3-acetamidopropanal + H2O2
- (2) N1-acetylspermine + O2 + H2O spermidine + 3-acetamidopropanal + H2O2
This enzyme also catalyses the reaction:
- N1,N12-diacetylspermine + O2 + H2O N1-acetylspermidine + 3-acetamamidopropanal + H2O2.