Non-selective_cation_channel-2_family
Non-selective cation channel-2 family
Group of transport proteins
Members of the Non-Selective Cation Channel-2 (NSCC2) Family (TC#1.A.15) have been sequenced from various yeast, fungal and animals species including Saccharomyces cerevisiae, Drosophila melanogaster and Homo sapiens.[1] These proteins are the Sec62 proteins, believed to be associated with the Sec61 and Sec63 constituents of the general protein secretory systems of yeast microsomes. They are also the non-selective (NS) cation channels of the mammalian cytoplasmic membrane.