PLEKHA1

PLEKHA1

PLEKHA1

Protein-coding gene in the species Homo sapiens

Pleckstrin homology domain-containing family A member 1 is a protein that in humans is encoded by the PLEKHA1 gene.[5][6][7]

Quick Facts Available structures, PDB ...

Interactions

PLEKHA1 has been shown to interact with MPDZ.[8]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000107679 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000040268 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR (Jan 2001). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities". Biochem J. 351 (Pt 1): 19–31. doi:10.1042/0264-6021:3510019. PMC 1221362. PMID 11001876.
  6. [6]
    Hogan A, Yakubchyk Y, Chabot J, Obagi C, Daher E, Maekawa K, Gee SH (Dec 2004). "The phosphoinositol 3,4-bisphosphate-binding protein TAPP1 interacts with syntrophins and regulates actin cytoskeletal organization". J Biol Chem. 279 (51): 53717–24. doi:10.1074/jbc.M410654200. PMID 15485858.
  7. [7]
    "Entrez Gene: PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1".
  8. [8]
    Kimber WA, Trinkle-Mulcahy L, Cheung PC, Deak M, Marsden LJ, Kieloch A, Watt S, Javier RT, Gray A, Downes CP, Lucocq JM, Alessi DR (Feb 2002). "Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo". Biochem. J. 361 (Pt 3): 525–36. doi:10.1042/0264-6021:3610525. PMC 1222335. PMID 11802782.

Further reading


Stub icon

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.
Share this article:

This article uses material from the Wikipedia article PLEKHA1, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.