Protopanaxadiol (PPD) is an organic compound that is an aglycone of ginsenosides, a group of steroid glycosides. It is a dammarane-type tetracyclic terpene sapogenin found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng).^[1][2]

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Protopanaxadiol

Names
IUPAC name Dammar-24-ene-3β,12β,20-triol
Systematic IUPAC name (1S,3aR,3bR,5aR,7S,9aR,9bR,11R,11aR)-1-[(2S)-2-Hydroxy-6-methylhept-5-en-2-yl]-3a,3b,6,6,9a-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthene-7,11-diol
Identifiers
CAS Number	7755-01-3 Y
3D model (JSmol)	Interactive image
Abbreviations	PPD
ChEBI	CHEBI:76237 N
ChEMBL	ChEMBL375563 N
ChemSpider	8095918 N
KEGG	C20715 Y
PubChem CID	9920281
UNII	P6717R7BP8 N
CompTox Dashboard (EPA)	DTXSID10952905
InChI InChI=1S/C30H52O3/c1-19(2)10-9-14-30(8,33)20-11-16-29(7)25(20)21(31)18-23-27(5)15-13-24(32)26(3,4)22(27)12-17-28(23,29)6/h10,20-25,31-33H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24-,25-,27-,28+,29+,30+/m0/s1 N Key: PYXFVCFISTUSOO-VUFVRDRTSA-N N InChI=1/C30H52O3/c1-19(2)10-9-14-30(8,33)20-11-16-29(7)25(20)21(31)18-23-27(5)15-13-24(32)26(3,4)22(27)12-17-28(23,29)6/h10,20-25,31-33H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24-,25-,27-,28+,29+,30+/m0/s1 Key: PYXFVCFISTUSOO-VUFVRDRTBZ
SMILES CC(=CCC[C@@](C)([C@H]1CC[C@@]2([C@@H]1[C@@H](C[C@H]3[C@]2(CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)O)C)O)C
Properties
Chemical formula	C30H52O3
Molar mass	460.743 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references

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The health effects of protopanaxadiol inside the human body is still unclear. One study suggests it has rapid, non-genomic effects on endothelial cells, binding to the glucocorticoid and oestrogen beta receptors. The study also showed an increase in intracellular calcium ion concentration.^[3]

• Protopanaxatriol