The Queen Elizabeth II Challenge Cup Stakes is a Grade I American thoroughbred horse race for three-year-old fillies over a distance of one and one-eighth miles on the turf held annually in October at Keeneland Race Course in Lexington, Kentucky during the fall meeting.

The race was inaugurated on October 11, 1984, in honour of the British monarch, Queen Elizabeth II, who attended the Keeneland races, during her private visit to Central Kentucky, and who presented a trophy on that date.^[1] The event was held on the dirt track over a distance of 1+1⁄16 miles with Sintra winning in a time of 1:432⁄5.^[1]

The following year the event was moved to the turf track.^[2]

The Queen Elizabeth II Challenge Cup was a Listed race in 1984 and 1985, and was upgraded to Grade III status in 1986.^[2] The event held this status for two runnings and was upgraded to Grade II.^[3] In 1991 was upgraded once more to Grade I.^[3]

It is an important prep race to the Breeders' Cup Filly & Mare Turf.

Time record:

• 1+1⁄8 miles: 1:45.81 – Memories of Silver (1996)
• 1+1⁄16 miles: 1:43.20 - Graceful Darby (1987)

Margins:

• 5 lengths – Graceful Darby (1987)

Most wins by an owner

• 2 – Henryk de Kwiatkowski (1985, 1986)
• 2 – Darby Dan Farm (1988, 1990)
• 2 – Stronach Stables (1999, 2000)

Most wins by a jockey

• 5 – John R. Velazquez (1995, 2008, 2014, 2016, 2019)

Most wins by a trainer

• 5 – Chad C. Brown (2012, 2018, 2019, 2021, 2022)

• List of American and Canadian Graded races

• Ten Things You Should Know about the QEII Challenge Cup at Hello Race Fans!