Regional 2 South Central is a level six league in the English rugby union system, one of twelve leagues, at this level. Originally part of the South West Division of the RFU, the league was transferred to the London & SE Division for season 2023–24, with a subsequent change of teams, with only five of the previous season's twelve teams remaining.^[1] Marlborough are the current champions and are promoted to Regional 1 South Central.

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Regional 2 South Central

Current season or competition: 2023–24 Regional 2 South Central
Sport	Rugby union
Instituted	2022
Number of teams	12
Country	England
Holders	Marlborough (2022–23)
Most titles	Marlborough (1 title)
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The season runs from September to April and comprises twenty-two rounds of matches, with each club playing each of its rivals home and away. The results of the matches contribute points to the league table as follows:

• 4 points are awarded for a win
• 2 points are awarded for a draw
• 0 points are awarded for a loss, however
• 1 losing (bonus) point is awarded to a team that loses a match by 7 points or fewer
• 1 additional (bonus) point is awarded to a team scoring 4 tries or more in a match

The club that finishes as champions is automatically promoted to Regional 1 South Central. Relegated teams drop down to a level seven league.

Regional 2 South Central has been transferred from the South West Division of the RFU to the London & SE Division and only five of last seasons teams remain. The Gloucestershire and Wiltshire teams (with the exception of Salisbury) were transferred to leagues in the South West Division.