Royal_Farm_virus
Royal Farm virus
Species of virus
Royal Farm virus, previously known as Karshi virus, was not viewed as pathogenic or harmful to humans. Although infected people suffer with fever-like symptoms, some people in Uzbekistan have reported with severe disease such as encephalitis and other large outbreaks of fever illness connected infection with the virus.[2]
The transmission cycle of members of the M-TBFV complex involves ixodid ticks and rodents. Not enough information about the development of the virus in rodent hosts is available, so many researchers have had to infect mice by needle or by allowing an infected tick to feed on them. Ticks exposed to Royal Farm virus remained efficient carriers even when tested about 8 years after their initial exposure. Because of this insight, these ticks may serve as a long-term maintenance mechanism for Royal Farm virus [3] Earlier studies suggest that the infection of a two-day-old white experimental mice with the virus results in deaths occurring 8–12 days after infection. Nine-day-old mice rarely die with similar exposure.[2]