Washington Redskins

Grant was selected by the Washington Redskins in the fifth round (142nd overall) of the 2014 NFL draft.^[6] On May 16, 2014, he signed a four-year, $2.36 million contract with the Redskins.^[7]

In 2015, Grant recorded his first career touchdown in the Week 7 win against the Tampa Bay Buccaneers which helped the Redskins comeback by its biggest deficit in Redskins franchise history.^[8] In the last game of the regular season against the Dallas Cowboys, Grant recorded his second career touchdown.^[9] In a Week 2 game against the Los Angeles Rams in September 2017, Grant caught a touchdown pass from quarterback Kirk Cousins late in the fourth quarter, helping the Redskins win by a score of 27–20.^[10]

Indianapolis Colts

On March 13, 2018, the Baltimore Ravens announced their intention to sign Grant to a four-year, $29 million contract with $14.5 million guaranteed.^[11] However, he failed his physical the next day, and the deal was voided making him a free agent.^[12][13] Grant ended up passing the Indianapolis Colts physical and signed a one-year, $5 million deal with them on March 20, 2018.^[14] In 2018, Grant appeared in 14 contests and made a career-high 10 starts for the Colts. In the regular season, he tallied 35 receptions for 334 yards, marks that each ranked fifth on the squad, while adding one receiving touchdown.

Oakland Raiders

On April 3, 2019, Grant signed with the Oakland Raiders.^[15] Grant made his debut with the Raiders in week 1 against the Denver Broncos. In the game, Grant made 3 catches for 16 yards in the 24–16 win.^[16] He was released on September 25, 2019.^[17]

Green Bay Packers

On October 16, 2019, Grant signed with the Green Bay Packers.^[18]

Calgary Stampeders

On February 3, 2021, Grant signed with the Calgary Stampeders of the Canadian Football League.^[19] He was placed on the suspended list on July 10, 2021.^[20] He was released on August 2, 2021.