SPRY1
SPRY1
Protein-coding gene in the species Homo sapiens
Protein sprouty homolog 1 is a protein that in humans is encoded by the SPRY1 gene.[5][6][7]
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- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Hacohen N, Kramer S, Sutherland D, Hiromi Y, Krasnow MA (January 1998). "sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways". Cell. 92 (2): 253–63. doi:10.1016/S0092-8674(00)80919-8. PMID 9458049. S2CID 498977.
- Haglund K, Schmidt MH, Wong ES, Guy GR, Dikic I (July 2005). "Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation". EMBO Reports. 6 (7): 635–41. doi:10.1038/sj.embor.7400453. PMC 1369112. PMID 15962011.
- Lim J, Wong ES, Ong SH, Yusoff P, Low BC, Guy GR (October 2000). "Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain". The Journal of Biological Chemistry. 275 (42): 32837–45. doi:10.1074/jbc.M002156200. PMID 10887178.
- Egan JE, Hall AB, Yatsula BA, Bar-Sagi D (April 2002). "The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins". Proceedings of the National Academy of Sciences of the United States of America. 99 (9): 6041–6. Bibcode:2002PNAS...99.6041E. doi:10.1073/pnas.052090899. PMC 122898. PMID 11983899.
- Hanafusa H, Torii S, Yasunaga T, Nishida E (November 2002). "Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway". Nature Cell Biology. 4 (11): 850–8. doi:10.1038/ncb867. PMID 12402043. S2CID 31064800.
- Di Y, Li J, Zhang Y, He X, Lu H, Xu D, et al. (June 2003). "HCC-associated protein HCAP1, a variant of GEMIN4, interacts with zinc-finger proteins". Journal of Biochemistry. 133 (6): 713–8. doi:10.1093/jb/mvg091. PMID 12869526.
- Wang L, Ji C, Wu H, Xu J, Wu Q, Dai J, et al. (November 2003). "Identification and expression analysis of a novel splice variant of human Sprouty1 gene". International Journal of Molecular Medicine. 12 (5): 783–7. doi:10.3892/ijmm.12.5.783. PMID 14533010.
- Anteby EY, Natanson-Yaron S, Greenfield C, Goldman-Wohl D, Haimov-Kochman R, Holzer H, Yagel S (July 2005). "Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching". Placenta. 26 (6): 476–83. doi:10.1016/j.placenta.2004.08.008. PMID 15950061.
- Cabrita MA, Jäggi F, Widjaja SP, Christofori G (September 2006). "A functional interaction between sprouty proteins and caveolin-1". The Journal of Biological Chemistry. 281 (39): 29201–12. doi:10.1074/jbc.M603921200. PMID 16877379.
- Fritzsche S, Kenzelmann M, Hoffmann MJ, Müller M, Engers R, Gröne HJ, Schulz WA (September 2006). "Concomitant down-regulation of SPRY1 and SPRY2 in prostate carcinoma". Endocrine-Related Cancer. 13 (3): 839–49. doi:10.1677/erc.1.01190. PMID 16954433.
- Schaaf G, Hamdi M, Zwijnenburg D, Lakeman A, Geerts D, Versteeg R, Kool M (January 2010). "Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene". Cancer Research. 70 (2): 762–71. doi:10.1158/0008-5472.CAN-09-2532. PMID 20068162.
- Charles NJ, Huebert RC, Lee S, Adhikari N, Polster S, Rider JE, et al. (September 2010). "Targeted Sprouty1 overexpression in cardiac myocytes does not alter myocardial remodeling or function". Molecular and Cellular Biochemistry. 342 (1–2): 57–62. doi:10.1007/s11010-010-0468-8. PMC 2923832. PMID 20461448.
- SPRY1 human gene location in the UCSC Genome Browser.
- SPRY1 human gene details in the UCSC Genome Browser.
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