Samuel or Sam Cooke may refer to:

• Samuel Cooke (Australian politician) (1847–1929)
• Sam Cooke (1931–1964), American singer
• Samuel Cooke (judge) (1912–1978), English judge
• Sam Cooke (model) (born 1985), English glamour model
• Sam Cooke (Australian footballer) (1883–1966), Australian rules footballer
• S. S. Cooke (Samuel Stephen Cooke Sr., 1879–1944), college football coach
• S. N. Cooke (Samuel Nathaniel Cooke Jr., 1883–1964), English architect
• Samuel Cooke and Co, oil and fuel delivery and manufacture service
• Sir Samuel Cooke, 1st Baronet (c. 1690–1758), Anglo-Irish politician

• Samuel Cook (disambiguation)
• Cooke (surname)
• Sam Koch, pronounced the same way

This disambiguation page lists articles about people with the same name.
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