Sir Charles Talbot, 2nd Baronet (8 November 1751 – 3 November 1812) was a British politician.

A member of a junior branch of the Talbot family headed by the Earl of Shrewsbury, Talbot was the son of Sir Charles Henry Talbot, 1st Baronet, son of Major-General Sherrington Talbot, son of William Talbot, Bishop of Durham. Charles Talbot, 1st Baron Talbot was his uncle and William Talbot, 1st Earl Talbot, his cousin.^{[citation needed]} He sat as Member of Parliament for Weobly from 1800 to 1802,^[1] for Rye from 1803 to 1806^[2] and for Bletchingley in 1812.^[3]

Talbot never married. He died in November 1812, aged 60, and was succeeded in the title by his younger brother, George.^{[citation needed]}