South Carolina Highway 105 (SC 105) is a 33.220-mile-long (53.462 km) state highway in the U.S. state of South Carolina. The highway connects rural areas of Union and Cherokee counties.

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South Carolina Highway 105
Route information
Maintained by SCDOT
Length	33.220 mi[1][2] (53.462 km)
Major junctions
South end	SC 49 south of Robat
Major intersections	US 29 / SC 18 / SC 150 in Gaffney
North end	I-85 in Gaffney
Location
Country	United States
State	South Carolina
Counties	Union, Cherokee
Highway system
South Carolina State Highway System Interstate US State Scenic
← SC 102 → SC 107

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SC 105 begins at an intersection with SC 49 (Lockhart Highway) south of Robat, in rural parts of northeastern Union County. It travels to the north and almost immediately intersects SC 9 (Jonesville–Lockhart Highway). The highway gradually moves to a more westerly routing, while still traveling north. It crosses over the Pacolet River on an unnamed bridge, where it enters Cherokee County. In Saratt, it intersects SC 211 (Gowdeysville Road). The two highways travel concurrently to the east-northeast. They split in a rural area, with SC 105 traveling to the north-northwest. It goes through Wilkinsville and intersects SC 329 (Victory Trail Road). In the southern part of Gaffney, the highway begins a concurrency with SC 18 (Frederick Street) near Limestone College. The concurrency only lasts about 1,000 feet (300 m). It turns left onto Union Street, and follows that road until it meets College Drive. Then, it turns right, before turning left onto East Rutledge Avenue. It then turns left onto SC 150 (South Limestone Street). The two highways split when SC 105 turns right onto Corry Street. It then intersects U.S. Route 29 (US 29; Old Georgia Highway/South Granard Street). After a temporary departure from the city limits, where the highway passes a Freightliner plant, it meets its northern terminus, an interchange with Interstate 85. Here, the roadway continues as Hyatt Street.^[3][4]

Two connector routes of SC 105 exist in Cherokee County: One in Saratt carries Skull Shoals Road for 0.15 miles (0.24 km) and acts as the southern leg of the SC 105/SC 211 wye intersection; the other is located southeast of Draytonville near the intersection of SC 329, it is 0.35 miles (0.56 km) long and is a former segment of SC 105 carrying the name Wilkinsville Highway.^[5] Both are not signed with these special route numbers though the connector near Draytonville is signed as mainline southbound SC 105.^[3]

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