Stearoylethanolamide

Stearoylethanolamide

Stearoylethanolamide

Chemical compound

Stearoylethanolamide (SEA) is an endocannabinoid neurotransmitter.[1]

Quick Facts Names, Identifiers ...

Stearoylethanolamide (C20H41NO2; 18:0), also called N-(octadecanoyl)ethanolamine, is an N-acylethanolamine and the ethanolamide of octadecanoic acid (C18H36O2; 18:0) and ethanolamine (MEA: C2H7NO), and functionally related to an octadecanoic acid.[2]

Levels of SEA correlate with changes in pain intensity, indicating this SEA change, reflect the pain reduction effects of IPRP.[3]

References

  1. [1]
    Mauro Maccarrone, Riccardo Pauselli, Marianna Di Rienzo, Alessandro Finazzi-Agrò (2002). "Binding, degradation and apoptotic activity of stearoylethanolamide in rat C6 glioma cells". Biochem J. 366 (Pt 1): 137–144. doi:10.1042/BJ20020438. PMC 1222758. PMID 12010121.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. [2]
    PubChem. "N-(2-Hydroxyethyl)octadecanamide". pubchem.ncbi.nlm.nih.gov. Retrieved 2022-09-27.
  3. [3]
    Stensson, Niclas; Gerdle, Björn; Rönne-Petersén, Linn; Yang, Liu L.; Lavebratt, Catharina; Falkenberg, Torkel; Ghafouri, Bijar (2022-02-26). "Investigating the Long-Term Effect of an Interdisciplinary Multimodal Rehabilitation Program on Levels of Bioactive Lipids and Telomerase Activity in Blood from Patients with Chronic Pain". Journal of Clinical Medicine. 11 (5): 1291. doi:10.3390/jcm11051291. ISSN 2077-0383. PMC 8911430. PMID 35268382.


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