Stria_vascularis_of_cochlear_duct

Stria vascularis of cochlear duct

Stria vascularis of cochlear duct

Capillary in the outer wall of the cochlear duct

The stria vascularis of the cochlear duct is a capillary loop in the upper portion of the spiral ligament (the outer wall of the cochlear duct or scala media). It produces endolymph for the scala media in the cochlea.

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Structure

The stria vascularis is part of the lateral wall of the cochlear duct.[1] It is a somewhat stratified epithelium containing primarily three cell types:

  • marginal cells,[1] which are involved in K+ transport, and line the endolymphatic space of the scala media.
  • intermediate cells,[1] which are pigment-containing cells scattered among capillaries.
  • basal cells,[1] which separate the stria vascularis from the underlying spiral ligament.[2] They are connected to basal cells with gap junctions.[1]

The stria vascularis also contains pericytes, melanocytes, and endothelial cells.[3]: 2380  It also contains intraepithelial capillaries - it is the only epithelial tissue that is not avascular (completely lacking blood vessels and lymphatic vessels).[citation needed]

Function

The stria vascularis produces endolymph for the scala media, one of the three fluid-filled compartments of the cochlea.[4] This maintains the ion balance of the endolymph that surround inner hair cells and outer hair cells of the organ of Corti.[4] It secretes lots of K+,[1][4] and may also secrete H+.[1]

References

Public domain This article incorporates text in the public domain from page 1055 of the 20th edition of Gray's Anatomy (1918)

  1. [1]
    Marcus, Daniel C. (2012). "37 - Acoustic Transduction". Cell Physiology Source Book (4th ed.). Academic Press. pp. 649–668. doi:10.1016/B978-0-12-387738-3.00037-8. ISBN 978-0-12-387738-3.
  2. [2]
    Ross, Michael H. Histology : a text and atlas / Michael H. Ross, Wojech Pawlina., -6th ed. p 940.
  3. [3]
    Laiwani, Anil K.; Qian, Z. Jason (2021). "Chapter 150: Pharmacologic and Molecular Therapies of the Cochlear and Vestibular Labirynths". In Flint, Paul W.; Francis, Howard W.; Haughey, Bruce H.; Lesperance, Marci M.; Lund, Valerie J.; Robbins, K. Thomas; Thomas, J. Regan (eds.). Cummings Otolaryngology: Head and Neck Surgery (Seventh ed.). pp. 2380–2395.e5. ISBN 978-0-323-61179-4.
  4. [4]
    Hopkins, Kathryn (2015). "27 - Deafness in cochlear and auditory nerve disorders". Handbook of Clinical Neurology. Vol. 129. Elsevier. pp. 479–494. doi:10.1016/B978-0-444-62630-1.00027-5. ISBN 978-0-444-62630-1. ISSN 0072-9752. PMID 25726286.


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