Sulforhodamine_101
Sulforhodamine 101
Chemical compound
Sulforhodamine 101 (SR101) is a red fluorescent dye. In neurophysiological experiments which comprise calcium imaging methods, it can be used for a counterstaining of astrocytes to be able to analyze data from neurons separately.[1] However, in addition to labeling astrocytes, SR101 labels myelinating oligodendrocytes.[2] SR101 has been reported to affect excitability of neurons and should therefore be used with caution.[3]
A sulfonyl chloride derivative of sulforhodamine 101, known as Texas Red, is used for conjugation to a number of functional groups, especially primary amines.