Syringocystadenoma_papilliferum
Syringocystadenoma papilliferum
Medical condition
Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis.[1]
Lesions have a heterogeneous, non-distinctive appearance that ranges from skin-colored to pink-colored papules or plaques. Typically, lesions form in the head and neck area.[1]
Syringocystadenoma papilliferum can develop de-novo or within a nevus sebaceous.[4] Syringocystadenoma papilliferum tends to be seen in children. It is present at birth in approximately 50% of individuals affected, and it develops before puberty in the remaining 15%-30%.[4]