TAF4B

TAF4B

TAF4B

Protein-coding gene in the species Homo sapiens

Transcription initiation factor TFIID subunit 4B is a protein that in humans is encoded by the TAF4B gene.[5][6][7]

Quick Facts Available structures, PDB ...

Function

TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which is involved in the initiation of gene transcription by RNA polymerase II (see MIM 180660).[supplied by OMIM][7]

Interactions

TAF4B has been shown to interact with RELA.[8]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000141384 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000054321 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Dikstein R, Zhou S, Tjian R (Nov 1996). "Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130". Cell. 87 (1): 137–46. doi:10.1016/S0092-8674(00)81330-6. PMID 8858156. S2CID 10194253.
  6. [6]
    Yamit-Hezi A, Nir S, Wolstein O, Dikstein R (Jul 2000). "Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes". J. Biol. Chem. 275 (24): 18180–7. doi:10.1074/jbc.275.24.18180. PMID 10849440.
  7. [7]
    "Entrez Gene: TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa".
  8. [8]
    Yamit-Hezi A, Dikstein R (Sep 1998). "TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB". EMBO J. 17 (17): 5161–9. doi:10.1093/emboj/17.17.5161. PMC 1170844. PMID 9724652.

Further reading


Stub icon

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by expanding it.
Share this article:

This article uses material from the Wikipedia article TAF4B, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.