TB-21007

TB-21007

TB-21007

Chemical compound


TB-21007 is a nootropic drug which acts as a subtype-selective inverse agonist at the α5 containing GABAA receptors.[1][2]

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See also


References

  1. Chambers MS, Atack JR, Bromidge FA, Broughton HB, Cook S, Dawson GR, et al. (March 2002). "6,7-Dihydro-2-benzothiophen-4(5H)-ones: a novel class of GABA-A alpha5 receptor inverse agonists". Journal of Medicinal Chemistry. 45 (6): 1176–9. doi:10.1021/jm010471b. PMID 11881985.
  2. Chambers MS, Atack JR, Broughton HB, Collinson N, Cook S, Dawson GR, et al. (May 2003). "Identification of a novel, selective GABA(A) alpha5 receptor inverse agonist which enhances cognition". Journal of Medicinal Chemistry. 46 (11): 2227–40. doi:10.1021/jm020582q. PMID 12747794.

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