Template:Major_side_effects_of_bicalutamide_alone
Template:Major side effects of bicalutamide alone
More information Frequency, Class of effect ...
Frequency | Class of effect | Effect |
---|---|---|
Very common (≥10%) | Reproductive system and breast disorders | • Breast tenderness[lower-alpha 1] • Gynecomastia[lower-alpha 1] |
Common (1–10%) | General and psychiatric disorders | • Asthenia • Decreased libido • Erectile dysfunction • Hot flashes |
Skin and subcutaneous tissue disorders |
• Decreased body hair | |
Hepato-biliary disorders | • Elevated liver enzymes[lower-alpha 2] | |
Uncommon (0.1–1%) | Immune system disorders and hypersensitivity reactions | • Angioedema • Hives |
Rare (<0.1%) or unknown | Respiratory disorders | • Lung disease[lower-alpha 3] |
Skin and subcutaneous tissue disorders | • Sensitivity to light | |
Hepato-biliary disorders | • Liver toxicity[lower-alpha 3] | |
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References
- Mcleod DG (September 2002). "Emerging role of adjuvant hormonal therapy". Urology. 60 (3 Suppl 1): 13–20, discussion 21. doi:10.1016/S0090-4295(02)01562-5. PMID 12231039.
- "Bicalutamide" (PDF). Richmond Hill, Ontario: Nu-Pharm Inc. October 2009.
- Bennett CL, Raisch DW, Sartor O (October 2002). "Pneumonitis associated with nonsteroidal antiandrogens: presumptive evidence of a class effect". Annals of Internal Medicine. 137 (7): 625. doi:10.7326/0003-4819-137-7-200210010-00029. PMID 12353966.
An estimated 0.77% of the 6,480 nilutamide-treated patients, 0.04% of the 41,700 flutamide-treated patients, and 0.01% of the 86,800 bicalutamide-treated patients developed pneumonitis during the study period.
- Molina Mancero G, Picón X, Di Tullio F, Ernst G, Dezanzo P, Salvado A, Chertcoff JF (October 2016). "Neumonía intersticial inducida por bloqueo androgénico máximo como tratamiento de cáncer de próstata avanzado" [Fatal interstitial lung disease associated with maximum androgen blockade. Report of one case]. Revista médica de Chile (in Spanish). 144 (10): 1356–1359. doi:10.4067/S0034-98872016001000017. PMID 28074993.
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