Titusville High School is part of the Brevard Public Schools System. It is located at 150 Terrier Trail South, Titusville, Florida.

In 1927, Titusville High School was founded at the current location, the first building devoted solely to high school classes in the city. The Spanish-style structure featured terrazzo floors, brick halls, an auditorium, cafeteria, a large second-floor library, and one-story wings housing industrial arts and home economics departments. Over the entrance was a bell tower, which was reproduced in smaller form as a monument when the building was demolished in 1972. None of the original structure remains.

The school was partially integrated in 1966, and fully integrated in 1967 with African-American students coming from the previously all-black school, the Andrew J. Gibson High School.^[3]

The campus contains several buildings: the two-story Dorothy S. Wise Instructional Building; the Science, Art, and Health Occupations Building; Fine and Performing Arts Buildings; Cafeteria, Gym, Media Center and Administrative offices.

A new football stadium was completed in mid-2007. Two buildings were constructed in 2008: An Administrative/Science/Freshman Center and a Performing Arts building.

Its primary sports rival is Astronaut High School.^[4]

• Joe DeForest (1983), former professional football player and college coach^[8]
• Bernard Giles (drop out), serial killer and rapist^[9]
• Michaela Hahn (2011), former professional soccer player^[10]
• J. T. Hassell (transferred), NFL safety for the New York Jets^[11][12]
• Charlie Huggins (1965), retired U.S. Army colonel, former president of the Alaska Senate^[13]
• John Jurasek (2015), YouTube personality, food critic and radio host^[14]
• Mitzi Kremer (1986), 1988 US Olympic swimming medalist^[15]
• Gerald White (1983), former professional football player^[16]
• Eugene M. Davis (1970), actor^[17]

• Jack Wilson, two-time Florida state champion high school basketball coach & former Anderson University basketball player^[18]