VUAA1

VUAA1

VUAA1

Chemical compound


VUAA1 is a chemical compound that works by over activating an insect's olfactory senses causing a repellent effect. It is considered to be an Orco allosteric agonist.[1] It was discovered at Vanderbilt University[2] with research being partially funded by the Bill and Melinda Gates Foundation.[3]

Quick Facts Names, Identifiers ...

VUAA1 is an agonist believed to work by overloading an insect's odorant receptors. It may be 1000 times stronger than DEET[4] and may lead to, "a powerful new family of compounds that can be used to disrupt the destructive behaviors of nuisance insects, agricultural pests, and disease vectors alike."[5]

VUAA1 has also been shown to stimulate mosquito sperm motility, thus showing a link between a mosquito's sense of smell and reproduction.[6]


References

  1. Medicine, Vanderbilt University School of. "Allosteric antagonism of insect odorant receptor ion channels. | Chemical Synthesis Core". medschool.vanderbilt.edu. Retrieved 2016-06-02.
  2. Jones, P. L.; Pask, G. M.; Rinker, D. C.; Zwiebel, L. J. (2011). "Functional agonism of insect odorant receptor ion channels". Proceedings of the National Academy of Sciences. 108 (21): 8821–5. Bibcode:2011PNAS..108.8821J. doi:10.1073/pnas.1102425108. PMC 3102409. PMID 21555561.
  3. Doug Gross (5 May 2014). "A bug repellent that could save lives - CNN.com". CNN. Retrieved 2016-06-02.

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